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Risk factors for cholesterol stones and pigment stones

Gallstones (Cholelithiasis)

Gallstones are frequently asymptomatic but can cause biliary colic (right upper quadrant pain due to impacted stones). Diagnosis is by U/S and remember that majority of stones are not radiopaque. Complications include cholecystitis,  choledocholithiasis (calculi within the biliary tract), biliary tract obstruction, pancreatitis and cholangitis.

Cholestrol stones are composed mostly of cholesterol monohydrate. The incidence increases with age. Risk factors include female gender, obesity, pregnancy, oral contraceptives and hormone replacement therapy. Native American Pima and Navajo Indians have an increased incidence of cholesterol gallstones.

Pigmented bilirubinate stones are composed of calcium salts and unconjugated bilirubin. Risk factors are chronic hemolytic anemias, cirrhosis, bacterial infection, and parasites (Ascaris or Clonorchis (Opisthorchis) sinensis).

Cholesterol stones explained in the video below:

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